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Neurotransmitter treatment could improve brain function in Parkinson's

Tuesday 15th November 2011

Eliminating one of the neurotransmitters in the part of the brain associated with Parkinson's disease could improve brain function in patients without any major side-effects, according to a recent study at the University of Western Ontario.

The team used genetic techniques to eliminate the secretion of acetycholine in mice, demonstrating that neurons using the compound were also responsible for secreting the neurotransmitter glutamate.

Elimination of acetycholine secretion had a positive effect on the actions of dopamine, which could lead to better treatments for Parkinson's disease patients.

"We suspect there will be improvement because in Parkinson's disease, in addition to the loss of dopamine, this group of neurons that secrete acetylcholine becomes abnormally hyperactive," said Dr Marco Prado of the university.

A recent study at Cardiff University also found that patients could be trained to control areas of the brain associated with movement, improving motor function using just the power of thinking.

Posted by Alex Franklin StortfordADNFCR-1780-ID-801208295-ADNFCR

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