Scientists 'uncover potential drug candidates for cystic fibrosis'
Tuesday 1st November 2011
Scientists have discovered a potential new drug candidates for cystic fibrosis and other diseases, according to new research.
A study published in the FASEB Journal explained how researchers used high-throughput screening to detect small-molecule drug candidates which help cells to bypass defective channels that usually move salt and water through cell membranes.
The drug candidates activate an alternative chloride channel called TMEM16A that could be effective in treating certain conditions, including cystic fibrosis, dry eye and dry mouth diseases, and slow-transit constipation.
Authors believe that further pre-clinical development of the chloride channel activators identified in the study could lead to new therapies for these conditions.
"Scientists have known for decades that cells have more than one way to move salt and water. Indeed, over the years many useful drugs have been developed that influence these movements in the heart and kidneys," said Gerald Weissman, editor-in-chief of the journal.
Posted by Alex Franklin Stortford
Related articles
Chemical to tackle breast cancer found in celery
Doctors and those in biomedical science jobs have long been searching for a definitive treatment to help treat breast cancer, but...
Thursday 17th May 2012
Prostate cancer drug set to be approved
A prostate cancer drug is set to be approved and put into use across NHS services after previously being rejected. The...
Wednesday 16th May 2012
Blindness could be treated with diabetes drug
Blindness is one condition that many people fear, the debilitating effect that it has can change a person's life forever. ...
Wednesday 9th May 2012
Related Biomedical-Science Jobs
Experienced BMS in Haematology needed for a locum opportunity to work in the North of England. Working full time hours within...
Full infoMediplacements are currently seeking experienced Biomedical Scientists for both locum and permanent vacancies across the Scotland,...
Full infoNorth West England based locum BMS' required!We are currently recruiting for experienced Biomedical Scientists for both locum...
Full info