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Gene variation 'predicts mental decline'

Tuesday 25th October 2011

Gene variation is able to predict the rate of age-related decline in cognitive performance, researchers have found.

A study published in journal Translational Psychiatry revealed that having one version of a single gene doubled the rate at which the participants' mental performance declined over time, compared to those with a different coding of the gene.

While this genetic variation has been linked to several psychiatric disorders in previous studies, this is the first time it has been studied with regards to a healthy, ageing brain.

The study also found a significant age-related decline in the size of key brain region the hippocampus in participants carrying this polymorphism.

While the study was carried out on experienced airline pilots, the results do not apply only to those in this occupation, according to senior study author Ahmad Salehi.

"This gene-associated difference may apply not only to pilots but also to the general public, for example in the ability to operate complex machinery," he said.

Written by James Puckle
 ADNFCR-1780-ID-800775881-ADNFCR

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