Biomedical study suggests PSA could predict prostate cancer growth
Tuesday 18th January 2011
A group of researchers in biomedical science jobs have demonstrated that the production of prostate specific antigen (PSA) could be connected to tumour growth.
In what the Duke University Medical Center research team claims to be the first discovery of its kind, scientists found that the antibody can move outside of cancerous cells and forms a complex capable of binding to a specific receptor.
This process can stimulate cancer cell growth, with scientists confident that the findings strengthen the argument for measuring PSA as a "marker of tumour progression".
Commenting on the findings, published in the Journal of Biological Chemistry, lead researcher Sal Pizzo explained: "If you were a cancer cell, you would like to turn on cell growth, turn off the process of death by cell apoptosis and you'd like to be able to migrate, and when the α2M antibody binds with the protease PSA molecule, all of that happens."
Recent research published in the Journal of Clinical Oncology suggested that exercise may lower the risk of death for men with prostate cancer, leading researchers from the Harvard School of Public Health to recommend patients add physical activity to their daily routine.
Written by Angela Newbury
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