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Biomedical scientists identify cancer gene

Thursday 22nd April 2010

A gene that could be behind hereditary breast and ovarian cancer has been identified by biomedical scientists.

Researchers led by Professor Alfons Meindl of the University of Technology Munich noted that RAD51C is essential for the repair of DNA within cells, with mutations causing the disease.

In cases where mutations have occurred, women were shown to be at 60 to 80 per cent risk of developing breast cancer, while the risk of ovarian cancer was 20 to 40 per cent.

One of the authors, the University Hospital of Cologne's Dr Rita Schmutzler, said the team is optimistic it will be possible to determine the chances of individuals getting the diseases.

"These risk predictions will allow the offering of tailored prevention and small meshed early recognition programmes," she said. "Risk-aligned prevention will become a new clinical area."

Last week, scientists in Israel suggested a voice test could allow sufferers of Parkinson's disease to be identified years earlier than is currently the case.

Written by Martin Lambert
ADNFCR-1780-ID-19736571-ADNFCR

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