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Biomedical scientists make ovary gene discovery

Friday 11th December 2009

A gene which keeps ovaries producing female hormones has been identified by biomedical scientists.

The discovery is said to important because it may mean that a baby's sex is not solely determined by X and Y chromosomes found in sperm, the Daily Mail reports.

A team of British and German researchers focussed on examining genes known as Sox9 and FoxL2.

They found that when they used a trick to switch off Sox9 in adult female mice, the other gene came into action.

This has the effect of switching the ovary off and it starts effectively turning into a testicle, producing the male hormone testosterone.

Co-author Robin Lovell-Badge from the Medical Research Council's National Institute for Medical Research in London - which is a collegiate organisation dedicated to studying important questions about the life processes - said we take it for granted that we maintain the sex we are born with.

"But this work shows that the activity of a single gene, FoxL2, is all that prevents adult ovary cells from turning into cells found in the testes," he added.

Written by Angela Newbury
ADNFCR-1780-ID-19508692-ADNFCR

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